Does large endometrioma per se increase AMH level?

Women with endometriosis, especially those endometrioma, present a considerable challenge for ovarian reserve appraisal. This diagnostic difficulty arises from several fundamental questions inherently linked to patient management: the potential influence of endometrioma on reserve; adverse effect surgery and adequacy established biomarkers, anti-Müllerian hormone antral follicle count, appraise accurately in these women. Until recently, key argument was that development growth endometriomas is associated progressive damage normal tissue, resulting concomitant reduction serum AMH levels. Contrary this widely accepted position; recent studies have reported that, women no previous history surgery, levels were increased large endometriomas. These findings are surprising and, if replicated, would substantial clinical implications. In commentary, we would, however, urge caution before reports lead systematic changes practice, recommend urgent replication as finding linking high seems be biologically implausible, contradicts existing extensive body research.